Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007854 | 0.80 | POLB (0.50) | TDP1TSHRKMT2AMEN1CA1 | |
| SCHEMBL27544454 | 0.80 | TDP1 (0.55) | TDP1SRD5A2TSHRTP53KMT2A | |
| SCHEMBL4543337 | 0.78 | ESR1 (0.50) | TDP1FBP1 | |
| SCHEMBL20680909 | 0.77 | KDM4E (0.45) | TDP1TSHRKMT2AALDH1A1 | |
| SCHEMBL264411 | 0.77 | KDM4E (0.45) | TDP1TSHRKMT2AALDH1A1 | |
| SCHEMBL2577243 | 0.77 | TDP1 (0.52) | TDP1SRD5A2TSHRTP53KMT2A | |
| 4-Nitrobenzoic Acid SCHEMBL7727849 | 0.77 | TDP1 (0.72) | TDP1SRD5A2TSHRRXRARXRB | |
| SCHEMBL17018447 | 0.75 | ACHE (0.48) | TDP1TSHRKMT2AFBP1ALDH1A1 | |
| SCHEMBL372015 | 0.74 | TSHR (0.60) | SRD5A2TSHRTP53RXRARXRB | |
| SCHEMBL31192242 | 0.74 | TSHR (0.60) | SRD5A2TSHRTP53RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212375-B1 | MODERATED REDUCTION REACTIONS FOR PRODUCING ARYLHYDROXYLAMINES | MicroSi, Inc. (a Delaware corporation) (US) | 1993-06-16 | — | — | EP | claimed |
| US-4723030-A | ACID CATALYTIC HYDROGENATION OF NITROAROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1988-02-02 | — | — | US | claimed |
| US-4709107-A | Process for producing nitrones | GENERAL ELECTRIC COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| EP-0212375-A1 | Moderated reduction reactions for producing arylhydroxylamines | MicroSi, Inc. (a Delaware corporation) (US) | 1987-03-04 | — | — | EP | claimed |
| US-20100009269-A1 | HOLOGRAPHIC RECORDING MEDIA | GENERAL ELECTRIC COMPANY (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100010262-A1 | COMPOSITIONS AND METHOD FOR MAKING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2010-01-14 | — | — | US | disclosed |
| EP-0212375-B1 | MODERATED REDUCTION REACTIONS FOR PRODUCING ARYLHYDROXYLAMINES | MicroSi, Inc. (a Delaware corporation) (US) | 1993-06-16 | — | — | EP | disclosed |
| US-4723030-A | ACID CATALYTIC HYDROGENATION OF NITROAROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| US-4709107-A | Process for producing nitrones | GENERAL ELECTRIC COMPANY (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0212375-A1 | Moderated reduction reactions for producing arylhydroxylamines | MicroSi, Inc. (a Delaware corporation) (US) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010262-A1 | COMPOSITIONS AND METHOD FOR MAKING THEREOF | C5, C1R, CBR3 | TDP1 2905/4885SRD5A2 1677/4885TSHR 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.