Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264411 | 1.00 | KDM4E (0.45) | KDM4EMAPTKMT2ANPSR1TDP1 | |
| SCHEMBL188305 | 0.84 | TSHR (0.39) | KDM4EMAPTKMT2ANPSR1TDP1 | |
| SCHEMBL11207492 | 0.82 | CALM1 (0.43) | KDM4EMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL17018447 | 0.79 | ACHE (0.48) | MAPTKMT2ANPSR1TDP1ALDH1A1 | |
| SCHEMBL4751040 | 0.77 | KDM4E (0.42) | KDM4EMAPTKMT2ANPSR1TDP1 | |
| SCHEMBL8094320 | 0.77 | KMT2A (0.42) | KDM4EMAPTKMT2ANPSR1TDP1 | |
| SCHEMBL11743677 | 0.77 | KMT2A (0.50) | KDM4EMAPTKMT2ANPSR1TDP1 | |
| SCHEMBL4543337 | 0.77 | ESR1 (0.50) | MAPTTDP1LMNACYP2D6 | |
| SCHEMBL264810 | 0.77 | ADRB2 (0.46) | MAPTKMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL12983360 | 0.77 | CYP1A2 (0.39) | KDM4EMAPTKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658152-A1 | FRUIT EXTRACT AND USES THEREOF | The University Of Nottingham (GB) | 2020-06-03 | — | — | EP | claimed |
| WO-2019021008-A1 | FRUIT EXTRACT AND USES THEREOF | THE UNIVERSITY OF NOTTINGHAM (GB) | 2019-01-31 | — | — | WO | claimed |
| EP-4210503-A1 | FLORAL WATER FROM COFFEE FLOWERS | Société des Produits Nestlé S.A. (CH) | 2023-07-19 | — | — | EP | disclosed |
| EP-4182305-A1 | NEMATICIDE COMPOUNDS, COMPOSITIONS, AND METHODS OF THEIR MAKING AND USE | Iowa State University Research Foundation, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022053605-A1 | FLORAL WATER FROM COFFEE FLOWERS | Société des Produits Nestlé S.A. (CH) | 2022-03-17 | — | — | WO | disclosed |
| WO-2022015821-A1 | NEMATICIDE COMPOUNDS, COMPOSITIONS, AND METHODS OF THEIR MAKING AND USE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| EP-3658152-A1 | FRUIT EXTRACT AND USES THEREOF | The University Of Nottingham (GB) | 2020-06-03 | — | — | EP | disclosed |
| WO-2019021008-A1 | FRUIT EXTRACT AND USES THEREOF | THE UNIVERSITY OF NOTTINGHAM (GB) | 2019-01-31 | — | — | WO | disclosed |