Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.50 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761718 | 0.89 | DGAT1 (0.43) | DGAT1CSGALNACT1CYP2C9RIPK1TP53 | |
| Trifluoroacetic Acid SCHEMBL3391046 | 0.88 | DGAT1 (0.60) | DGAT1CSGALNACT1PDE10A | |
| SCHEMBL3387517 | 0.86 | DGAT1 (0.50) | DGAT1CSGALNACT1PDE10ASMN1; SMN2NPC1 | |
| SCHEMBL1761824 | 0.86 | DGAT1 (0.64) | DGAT1CSGALNACT1PDE10A | |
| SCHEMBL3389661 | 0.83 | DGAT1 (0.54) | DGAT1CSGALNACT1PDE10ANPC1CYP2C9 | |
| SCHEMBL12648322 | 0.79 | DGAT1 (0.47) | DGAT1CSGALNACT1PDE10ASMN1; SMN2NPC1 | |
| SCHEMBL1761354 | 0.79 | DGAT1 (0.44) | DGAT1CSGALNACT1MAPT | |
| SCHEMBL1761407 | 0.77 | DGAT1 (0.42) | DGAT1CSGALNACT1MAPTPOLBTRPV1 | |
| Trifluoroacetic Acid SCHEMBL1761714 | 0.77 | DGAT1 (0.51) | DGAT1CSGALNACT1 | |
| SCHEMBL1761670 | 0.76 | DGAT1 (0.42) | DGAT1CSGALNACT1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805156-B1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-12-22 | — | — | EP | disclosed |