Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294823 | 0.74 | — | — | |
| SCHEMBL1376057 | 0.73 | MAPK1 (0.44) | LMNABLMPMP22 | |
| SCHEMBL4632184 | 0.72 | CRBN (0.39) | — | |
| SCHEMBL3392541 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL11238901 | 0.71 | MAPK1 (0.42) | LMNABLMPMP22 | |
| SCHEMBL10017926 | 0.67 | — | — | |
| SCHEMBL4202941 | 0.67 | — | — | |
| SCHEMBL15541624 | 0.65 | PKM (0.31) | PKM | |
| SCHEMBL15540948 | 0.65 | PKM (0.31) | PKM | |
| SCHEMBL19920645 | 0.64 | PKM (0.39) | PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442970-A | Thiazole compounds as cannabinoid receptor ligands and uses thereof | ABBOTT LAB | 2012-05-09 | — | — | CN | claimed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | claimed |
| EP-2737901-B1 | Therapeutic Use of Compounds | UCL BUSINESS LTD (GB) | 2021-03-03 | — | — | EP | disclosed |
| EP-3636259-A1 | THERAPEUTIC USE OF COMPOUNDS | UCL BUSINESS LTD (GB) | 2020-04-15 | — | — | EP | disclosed |
| EP-2642990-B1 | THERAPEUTIC USE OF COMPOUNDS | UCL BUSINESS PLC (GB) | 2019-09-18 | — | — | EP | disclosed |
| US-9023844-B2 | Heterocyclylpyri (mi) dinylpyrazole as fungicidals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-20140256677-A1 | HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| EP-2737901-A1 | Therapeutic Use of Compounds | UCL Business PLC (GB) | 2014-06-04 | — | — | EP | disclosed |
| EP-2222165-B1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBVIE INC (US) | 2013-07-31 | — | — | EP | disclosed |
| US-20120264827-A1 | SULFANYLAMIDE DERIVATIVES, USES THEREOF AND COMPOSITIONS COMPRISING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-10-18 | — | — | US | disclosed |
| EP-2480527-A1 | SULFANYLAMIDE DERIVATIVES, USES THEREOF AND COMPOSITIONS COMPRISING THEM | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2012-08-01 | — | — | EP | disclosed |
| US-20060148861-A1 | Amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid | YISSUM RESEARCH DEVELOPEMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-07-06 | — | — | US | disclosed |
| EP-1603891-A1 | NEW AMIDE DERIVATIVES OF 2,2,3,3-TETRAMETHYLCYCLOPROPANE CARBOXYLIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-12-14 | — | — | EP | disclosed |
| US-6960687-B2 | Derivatives and pharmaceutical compositions of n-hydroxyalkyl tetramethylcyclopropane-carboxamide, having anti-epiletic, neurological, and CNS activity, and method for their preparation | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-11-01 | — | — | US | disclosed |
| US-20050131069-A1 | Derivatives and pharmaceutical compositions of n-hydroxyalkyl tetramethylcyclopropane-carboxamide, having anti-epiletic, neurological, and cns activity, and method for their preparation | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW (IL) | 2005-06-16 | — | — | US | disclosed |
| EP-1487787-A1 | DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS OF N-HYDROXYALKYL TETRAMETHYLCYCLOPROPANE-CARBOXAMIDE, HAVING ANTI-EPILEPTIC, NEUROLOGICAL, AND CNS ACTIVITY, AND METHOD FOR THEIR PREPARATION | Yissum Research Development Company of the Hebrew University of Jerusalem (IL) | 2004-12-22 | — | — | EP | disclosed |
| WO-2004076432-A1 | NEW AMIDE DERIVATIVES OF 2,2,3,3-TETRAMETHYLCYCLOPROPANE CARBOXYLIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-09-10 | — | — | WO | disclosed |
| WO-2003064374-A1 | DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS OF N-HYDROXYALKYL TETRAMETHYLCYCLOPROPANE-CARBOXAMIDE, HAVING ANTI-EPILEPTIC, NEUROLOGICAL, AND CNS ACTIVITY, AND METHOD FOR THEIR PREPARATION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-08-07 | — | — | WO | disclosed |
| US-5880157-A | ANTIEPILEPTIC AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-03-09 | — | — | US | disclosed |
| WO-1995021814-A1 | NOVEL DERIVATIVES OF TETRAMETHYLCYCLOPROPANE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256677-A1 | HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS | CCNY, NQO2, H1-0 | PKM 2090/4885LMNA 958/4885ALOX15 3985/4885 |
| US-20050131069-A1 | Derivatives and pharmaceutical compositions of n-hydroxyalkyl tetramethylcyclopropane-carboxamide, having anti-epiletic, neurological, and cns activity, and method for their preparation | SCN1A, MAG, SCN8A | PKM 1097/4885LMNA 482/4885ALOX15 1077/4885 |
| US-20060148861-A1 | Amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid | CNR2, GRIN2A, GRIN2C | PKM 1134/4885LMNA 2874/4885ALOX15 1256/4885 |
| US-20120264827-A1 | SULFANYLAMIDE DERIVATIVES, USES THEREOF AND COMPOSITIONS COMPRISING THEM | CNR2, SULT2A1, CYP2S1 | PKM 3838/4885LMNA 2408/4885ALOX15 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.