Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396913 | 0.89 | CHRM2 (0.51) | OPRM1CHRM2CHRM1KIF11CHRM3 | |
| SCHEMBL3392692 | 0.86 | OPRM1 (0.51) | OPRM1MIFCHRM2CHRM1KIF11 | |
| SCHEMBL27330636 | 0.84 | OPRM1 (0.48) | OPRM1MIFCHRM2CHRM1KIF11 | |
| SCHEMBL27965739 | 0.84 | ESR1 (0.52) | OPRM1CHRM2CHRM1KIF11CHRM3 | |
| SCHEMBL10452446 | 0.82 | KCNN4 (0.51) | OPRM1CHRM2CHRM1KIF11CHRM3 | |
| Phosphonic Acid SCHEMBL29035527 | 0.81 | CHRM2 (0.46) | OPRM1CHRM2CHRM1KIF11CHRM3 | |
| SCHEMBL10539630 | 0.78 | MIF (0.48) | MIFKIF11BCL2CYP1A2PPARA | |
| SCHEMBL4192907 | 0.77 | ESR1 (0.54) | CYP1A2SLC6A4KMT2AMEN1LMNA | |
| SCHEMBL11752498 | 0.77 | CHRM2 (0.51) | OPRM1CHRM2CHRM1KIF11CHRM3 | |
| SCHEMBL19031877 | 0.76 | CYP19A1 (0.43) | OPRM1CHRM2CHRM1CHRM3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054319-A2 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |