SCHEMBL11752498

SCHEMBL11752498

CCC(C(=O)C(CC)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.51
CHRM1 P11229 2/20 0.51
CHRM3 P20309 2/20 0.51
OPRM1 P35372 5/20 0.50
DRD3 P35462 3/20 0.50
DRD2 P14416 1/20 0.50
CYP2C19 P33261 2/20 0.47
HIF1A Q16665 1/20 0.47
GRIN2D O15399 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
DRD4 P21917 2/20 0.46
OPRD1 P41143 2/20 0.46
KCNH2 Q12809 2/20 0.46
CACNA1F O60840 1/20 0.46
ABCB1 P08183 1/20 0.46
CYP2B6 P20813 1/20 0.46
OPRK1 P41145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396913 0.86 CHRM2 (0.51) CHRM2CHRM1CHRM3OPRM1DRD3
SCHEMBL20607354 0.83 OPRM1 (0.66) CHRM2CHRM1CHRM3OPRM1DRD3
SCHEMBL4030430 0.83 MAPT (0.55) CHRM2CHRM1CHRM3OPRM1DRD3
Hydrochloric Acid SCHEMBL5252883 0.81 MAPT (0.53) CHRM2CHRM1CHRM3OPRM1DRD3
SCHEMBL6016876 0.79 OPRM1 (0.67) CHRM2CHRM1CHRM3OPRM1DRD3
Phosphonic Acid SCHEMBL29035527 0.79 CHRM2 (0.46) CHRM2CHRM1CHRM3OPRM1DRD3
SCHEMBL27382896 0.79 KCNN4 (0.60) CHRM2CHRM1CHRM3OPRM1DRD3
SCHEMBL7054463 0.79 CHRM2 (0.58) CHRM2CHRM1CHRM3OPRM1DRD3
SCHEMBL7788672 0.79 CHRM2 (0.46) CHRM2CHRM1CHRM3OPRM1DRD3
SCHEMBL27963581 0.79 CHRM2 (0.46) CHRM2CHRM1CHRM3OPRM1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042587-A PESTICIDES BASF AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed