Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393583 | 0.77 | TSHR (0.40) | KDM4EMEN1MAPTKMT2AHPGD | |
| SCHEMBL3394045 | 0.76 | MEN1 (0.34) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL3395257 | 0.70 | MEN1 (0.41) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL16308843 | 0.69 | MAPT (0.59) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL697151 | 0.62 | AKR1C1 (0.48) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL706765 | 0.62 | NR4A1 (0.42) | KDM4EMEN1MAPTKMT2ANR4A1 | |
| SCHEMBL28240863 | 0.61 | MEN1 (0.53) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| Bicarbonate SCHEMBL809258 | 0.61 | CYP2A6 (0.77) | KDM4ENR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL8112531 | 0.61 | AKR1C1 (0.52) | NR4A1NR4A2NR4A3KIF11CDC25B | |
| Naphthoic Acid SCHEMBL30401620 | 0.60 | NR4A1 (0.91) | KDM4EMEN1MAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229167-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | Merck Sharp & Dohme Corp. (US) | 2010-09-22 | — | — | EP | claimed |
| WO-2009078934-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2009-06-25 | — | — | WO | claimed |
| EP-2229167-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | Merck Sharp & Dohme Corp. (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009078934-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2009-06-25 | — | — | WO | disclosed |