Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 13/20 | 0.51 |
| ▸ | DDO | Q99489 | 5/20 | 0.51 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393601 | 0.94 | DAO (0.51) | DAODDOIDH1MAPTKDM4E | |
| SCHEMBL3396789 | 0.71 | DAO (0.63) | DAODDOIDH1 | |
| SCHEMBL3360565 | 0.71 | DAO (0.53) | DAODDO | |
| SCHEMBL3393710 | 0.71 | DAO (0.54) | DAODDOIDH1 | |
| SCHEMBL27297881 | 0.71 | TRPV4 (0.44) | DAOIDH1MAPTCYP1A2ALOX15 | |
| SCHEMBL3363129 | 0.69 | DAO (0.54) | DAODDO | |
| SCHEMBL16767846 | 0.68 | DAO (1.00) | DAODDOKDM4EALDH1A1 | |
| SCHEMBL3395521 | 0.68 | DAO (1.00) | DAODDOKDM4E | |
| SCHEMBL13814617 | 0.68 | KDM4E (0.44) | DAOIDH1MAPTCYP1A2ALOX15 | |
| SCHEMBL9389345 | 0.68 | CYP1A2 (0.38) | DAODDOMAPTCYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |