Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 10/20 | 0.63 |
| ▸ | DDO | Q99489 | 3/20 | 0.63 |
| ▸ | FASN | P49327 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392647 | 0.81 | FASN (0.47) | DAODDOFASNNOS3NOS1 | |
| SCHEMBL9393317 | 0.78 | FASN (0.57) | DAODDOFASN | |
| SCHEMBL3359541 | 0.77 | DAO (1.00) | DAODDO | |
| SCHEMBL1080585 | 0.77 | NOS3 (0.51) | NOS3NOS1NOS2PIN1IDH1 | |
| SCHEMBL11061371 | 0.76 | CDK5 (0.41) | DAODDOFASNNOS3NOS1 | |
| SCHEMBL3716513 | 0.76 | IDH1 (0.50) | FASNPIN1IDH1 | |
| SCHEMBL30905530 | 0.74 | NOS3 (0.53) | FASNNOS3NOS1NOS2PIN1 | |
| SCHEMBL118018 | 0.74 | NOS3 (0.53) | FASNNOS3NOS1NOS2PIN1 | |
| SCHEMBL16767847 | 0.74 | DAO (1.00) | DAODDO | |
| SCHEMBL15690449 | 0.74 | DAO (0.64) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |