SCHEMBL3391838

SCHEMBL3391838

COC(=O)C(=O)[C@]1(C(=O)O)CCCN1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3701124 0.95 NPSR1 (0.34) NPSR1CYP4F2CYP4A11
SCHEMBL1234317 0.79 ARG1 (0.33) ARG1ARG2
SCHEMBL774037 0.78 ARG1 (0.39) ARG1ARG2
Hydrochloric Acid SCHEMBL16993455 0.76 ARG1 (0.38) ARG1ARG2
SCHEMBL18076611 0.75 ARG1 (0.35) ARG1ARG2
SCHEMBL18076610 0.75 ARG1 (0.35) ARG1ARG2
SCHEMBL3934353 0.72 ARG1 (0.34) ARG1ARG2
SCHEMBL2900265 0.71 ARG1 (0.39) ARG1ARG2
SCHEMBL7313574 0.70 CYP4F2 (0.31) ARG1ARG2CYP4F2CYP4A11
SCHEMBL14246934 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2242838-A1 STEM-LIKE CELLS AND METHOD FOR REPROGRAMMING ADULT MAMMALIAN SOMATIC CELLS GliaMed, Inc. (US) 2010-10-27 EP disclosed
WO-2009079007-A1 STEM-LIKE CELLS AND METHOD FOR REPROGRAMMING ADULT MAMMALIAN SOMATIC CELLS GLIAMED, INC. (US) 2009-06-25 WO disclosed