Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774037 | 0.92 | ARG1 (0.39) | ARG1ARG2CYP2C19FFAR3 | |
| Hydrochloric Acid SCHEMBL16993455 | 0.90 | ARG1 (0.38) | ARG1ARG2FFAR3 | |
| SCHEMBL8993303 | 0.87 | FFAR3 (0.31) | ARG1ARG2FFAR3 | |
| SCHEMBL8371988 | 0.87 | FFAR3 (0.31) | ARG1ARG2FFAR3 | |
| SCHEMBL28200534 | 0.83 | — | — | |
| SCHEMBL4939341 | 0.80 | — | — | |
| SCHEMBL2900265 | 0.79 | ARG1 (0.39) | ARG1ARG2 | |
| SCHEMBL18076611 | 0.79 | ARG1 (0.35) | ARG1ARG2FFAR3 | |
| SCHEMBL18076610 | 0.79 | ARG1 (0.35) | ARG1ARG2FFAR3 | |
| SCHEMBL14246934 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899487-B | Method for producing 5-hydroxypiperidine-2-carboxylic acid | 株式会社API | 2018-10-19 | — | — | CN | disclosed |
| CN-107573277-A | The manufacture method of the formic acid of 5 hydroxy piperidine 2 | 株式会社API | 2018-01-12 | — | — | CN | disclosed |
| CN-105899487-A | Method for producing 5-hydroxypiperidine-2-carboxylic acid | 株式会社API | 2016-08-24 | — | — | CN | disclosed |
| US-20150011541-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2015-01-08 | — | — | US | disclosed |
| EP-2797887-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013097947-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610245-A1 | Pipecolate-sulfonamides for treatment of psychiatric disorders | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-07-03 | — | — | EP | disclosed |
| US-7572913-B2 | Inhibitors of Rho kinase; N-Benzyloxycarbonyl-4-[N''-(tert-butyloxycarbonyl)hydrazino]piperidine; 4-{[N''-(tert-butyloxycarbonyl)-N'-(1'-propyl)]hydrazino}piperidine | BIOAXONE THERAPEUTIQUE INC. (CA) | 2009-08-11 | — | — | US | disclosed |
| EP-1720874-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Bioaxone Therapeutique Inc. (CA) | 2006-11-15 | — | — | EP | disclosed |
| US-20050272751-A1 | 4-Substituted piperidine derivatives | BIOAXONE THERAPEUTIQUE INC. (CA) | 2005-12-08 | — | — | US | disclosed |
| WO-2005080394-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | BIOAXONE THERAPEUTIQUE INC. (CA) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272751-A1 | 4-Substituted piperidine derivatives | RHOC, PRPH, RHOT2 | ARG1 94/4885ARG2 62/4885CYP2C19 4564/4885 |
| US-20150011541-A1 | PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | SYNGR2, SLC18A2, SLC6A3 | ARG1 4491/4885ARG2 3713/4885CYP2C19 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.