Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495101 | 0.85 | DHODH (0.33) | DHODH | |
| SCHEMBL3391830 | 0.85 | DHODH (0.38) | DHODHKMT2AL3MBTL1ABCB1ABCC1 | |
| SCHEMBL3259325 | 0.77 | MAPT (0.42) | DHODHKMT2A | |
| SCHEMBL3263059 | 0.73 | TRPM8 (0.46) | KMT2AL3MBTL1 | |
| SCHEMBL13495117 | 0.69 | DHODH (0.38) | DHODHKMT2A | |
| SCHEMBL3262693 | 0.69 | ATM (0.42) | KMT2A | |
| SCHEMBL3262520 | 0.67 | MAPT (0.48) | — | |
| SCHEMBL21494398 | 0.64 | KMT2A (0.41) | KMT2AL3MBTL1ABCB1ABCC1 | |
| SCHEMBL29558738 | 0.63 | KMT2A (0.41) | KMT2AL3MBTL1 | |
| SCHEMBL3387939 | 0.62 | SLC5A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |