Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495117 | 0.85 | DHODH (0.38) | DHODHNPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL3391844 | 0.85 | DHODH (0.33) | DHODHKMT2AL3MBTL1ABCB1ABCC1 | |
| SCHEMBL3385375 | 0.79 | RAB9A (0.45) | DHODHNPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL3264381 | 0.74 | TRPM8 (0.43) | DHODHNPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL3263308 | 0.74 | NPSR1 (0.40) | DHODHNPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL3393032 | 0.73 | ATM (0.46) | NPSR1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3264346 | 0.72 | KDM4E (0.43) | NPSR1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3261663 | 0.72 | NPSR1 (0.45) | DHODHNPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL3260789 | 0.72 | NPSR1 (0.45) | DHODHNPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL3261292 | 0.72 | ALDH1A1 (0.46) | DHODHNPSR1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |