Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427913 | 0.95 | POLB (0.36) | KCNK3LMNASMN1; SMN2POLBSPHK1 | |
| SCHEMBL8427900 | 0.81 | SMN1; SMN2 (0.38) | KCNK3LMNASMN1; SMN2POLBTSHR | |
| SCHEMBL3969870 | 0.80 | LMNA (0.52) | KCNK3LMNASMN1; SMN2POLBTSHR | |
| SCHEMBL20143218 | 0.80 | LMNA (0.52) | KCNK3LMNASMN1; SMN2POLBTSHR | |
| SCHEMBL8246334 | 0.79 | POLB (0.34) | LMNASMN1; SMN2POLBKDM4ESPHK1 | |
| SCHEMBL8245000 | 0.79 | POLB (0.34) | LMNASMN1; SMN2POLBSPHK1HTT | |
| Hydrochloric Acid SCHEMBL28153235 | 0.79 | LMNA (0.51) | KCNK3LMNASMN1; SMN2POLBTSHR | |
| SCHEMBL3388069 | 0.78 | HTT (0.44) | KCNK3LMNASMN1; SMN2POLBTSHR | |
| SCHEMBL25833199 | 0.78 | HTT (0.44) | KCNK3LMNASMN1; SMN2POLBTSHR | |
| SCHEMBL2563563 | 0.78 | LMNA (0.38) | KCNK3LMNASMN1; SMN2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |