Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1260880 | 0.99 | HTR2C (0.43) | HTR2CHTR2BHTR2AHTR7ALPL | |
| SCHEMBL1967019 | 0.86 | HTR2C (0.51) | HTR2CHTR2BHTR2ASMN1; SMN2 | |
| SCHEMBL3388287 | 0.85 | HTR2C (0.53) | HTR2CHTR2BHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL1262177 | 0.85 | HTR2C (0.50) | HTR2CHTR2BHTR2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1262699 | 0.84 | HTR2A (0.52) | HTR2CHTR2BHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL1262185 | 0.83 | HTR2C (0.39) | HTR2CHTR2BHTR2AHTR7ASIC3 | |
| SCHEMBL3394336 | 0.81 | USP1 (0.43) | HTR2CHTR2BHTR2APARP1KDM4E | |
| SCHEMBL3419388 | 0.80 | PSD (0.42) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL1262796 | 0.80 | USP1 (0.42) | HTR2CHTR2BHTR2APARP1KDM4E | |
| Hydrochloric Acid SCHEMBL1261370 | 0.79 | PSD (0.41) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2010-07-14 | — | — | EP | disclosed |