Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 2/20 | 0.43 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1262796 | 0.99 | USP1 (0.42) | USP1WDR48HTR2CHTR2AHTR2B | |
| SCHEMBL1967019 | 0.86 | HTR2C (0.51) | HTR2CHTR2AHTR2BHTTCYP3A4 | |
| Hydrochloric Acid SCHEMBL1262177 | 0.85 | HTR2C (0.50) | HTR2CHTR2AHTR2BHTTCYP3A4 | |
| SCHEMBL3419388 | 0.85 | PSD (0.42) | HTR2CHTR2AHTR2BCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL1261370 | 0.84 | PSD (0.41) | HTR2CHTR2AHTR2BCYP3A4CYP2C9 | |
| SCHEMBL3392016 | 0.81 | HTR2C (0.44) | HTR2CHTR2AHTR2BSMN1; SMN2KDM4E | |
| SCHEMBL3388287 | 0.80 | HTR2C (0.53) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL1260880 | 0.80 | HTR2C (0.43) | HTR2CHTR2AHTR2BSMN1; SMN2KDM4E | |
| SCHEMBL4391037 | 0.79 | HTR2C (0.41) | HTR2CHTR2AHTR2BHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1262699 | 0.79 | HTR2A (0.52) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2010-07-14 | — | — | EP | disclosed |