Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156341 | 0.85 | MAPT (0.43) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL3260000 | 0.81 | KMT2A (0.48) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL17156158 | 0.76 | MAPT (0.46) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL17156146 | 0.74 | L3MBTL1 (0.47) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL13497077 | 0.74 | KCNH2 (0.41) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL17156249 | 0.72 | LPAR2 (0.41) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL17156325 | 0.71 | TTR (0.48) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL17156161 | 0.71 | DHODH (0.50) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL17156291 | 0.71 | MAPT (0.44) | MEN1KMT2AMAPTALOX12NPSR1 | |
| SCHEMBL17156183 | 0.69 | CCR4 (0.41) | MEN1KMT2AMAPTALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |