Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tributylmethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tributylmethylammonium SCHEMBL1627725 | 0.95 | BBOX1 (0.41) | LMNAPOLBMEN1GRK2KMT2A | |
| Tributylmethylammonium SCHEMBL1337147 | 0.93 | BBOX1 (0.40) | LMNAPOLBMEN1GRK2KMT2A | |
| Tributylmethylammonium SCHEMBL268725 | 0.91 | MEN1 (0.39) | LMNAPOLBMEN1GRK2KMT2A | |
| Tributylmethylammonium SCHEMBL1618259 | 0.88 | BBOX1 (0.40) | LMNAPOLBMEN1GRK2KMT2A | |
| Sulfuric Acid SCHEMBL2995826 | 0.86 | LSS (0.52) | KMT2ASLC22A1DNM1LSSTSHR | |
| Sulfuric Acid SCHEMBL4151447 | 0.86 | LSS (0.52) | KMT2ASLC22A1DNM1LSSTSHR | |
| Sulfuric Acid SCHEMBL29702465 | 0.86 | LSS (0.52) | KMT2ASLC22A1DNM1LSSTSHR | |
| Sulfuric Acid SCHEMBL31472472 | 0.86 | LSS (0.52) | KMT2ASLC22A1DNM1LSSTSHR | |
| Sulfuric Acid SCHEMBL29702571 | 0.86 | LSS (0.52) | KMT2ASLC22A1DNM1LSSTSHR | |
| Sulfuric Acid SCHEMBL29702366 | 0.86 | LSS (0.52) | KMT2ASLC22A1DNM1LSSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246651-A2 | Absorption heat pumps, absorption coolers and absorption heat transformers on a EMIM acetate / methanol basis | BASF SE (DE) | 2010-11-03 | — | — | EP | disclosed |