Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tributylmethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL6379103 | 0.94 | SLC22A1 (0.50) | MEN1KMT2ALMNAPOLBGRK2 | |
| Sulfuric Acid SCHEMBL6054968 | 0.91 | LSS (0.48) | KMT2ASLC22A1DNM1LSS | |
| Sulfuric Acid SCHEMBL2544115 | 0.91 | LSS (0.48) | KMT2ASLC22A1DNM1LSS | |
| Sulfuric Acid SCHEMBL6257863 | 0.91 | LSS (0.48) | KMT2ASLC22A1DNM1LSS | |
| Sulfuric Acid SCHEMBL781963 | 0.91 | LSS (0.48) | KMT2ASLC22A1DNM1LSS | |
| Sulfuric Acid SCHEMBL6261099 | 0.91 | LSS (0.48) | KMT2ASLC22A1DNM1LSS | |
| Sulfuric Acid SCHEMBL6405441 | 0.91 | LSS (0.48) | KMT2ASLC22A1DNM1LSS | |
| Tributylmethylammonium SCHEMBL3392205 | 0.91 | LMNA (0.39) | MEN1KMT2ALMNAPOLBGRK2 | |
| Tributylmethylammonium SCHEMBL1627727 | 0.90 | TP53 (0.41) | BBOX1SLC22A1DNM1TP53ENPP2 | |
| Tributylmethylammonium SCHEMBL1627725 | 0.90 | BBOX1 (0.41) | MEN1KMT2ALMNAPOLBGRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109504015-B | Electrochromic polymer material based on combination strategy and preparation of electrochromic device | 常州铱视光电科技有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-108949141-B | Preparation method of bistable electrochromic material and application of bistable electrochromic material in preparation of electrochromic device | 常州铱视光电科技有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-111117594-A | Electrochromic material based on dynamic metal-ligand complexation and electrochromic device | 吉林大学 | 2020-05-08 | — | — | CN | claimed |
| CN-109504015-A | Electrochromic polymeric compounds material based on combined strategy and prepare electrochromic device | 常州铱视光电科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-103328483-B | Process for preparing dithiine tetracarboximides | 拜耳知识产权有限责任公司 | 2016-09-14 | — | — | CN | claimed |
| US-8314236-B2 | Trazodone and trazodone hydrochloride in purified form | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2012-11-20 | — | — | US | claimed |
| US-20120142699-A1 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM | AZIENDE CHIM. RIUN. ANG. FRANC. A.C.R.A.F. S.P.A. (IT) | 2012-06-07 | — | — | US | claimed |
| US-8133893-B2 | Trazodone and trazodone hydrochloride in purified form | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2012-03-13 | — | — | US | claimed |
| US-7718579-B2 | Electrochemical deblocking using a hydrazine derivative | COMBIMATRIX CORPORATION (US) | 2010-05-18 | — | — | US | claimed |
| EP-2178850-A1 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) | 2010-04-28 | — | — | EP | claimed |
| WO-2009019133-A1 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2009-02-12 | — | — | WO | claimed |
| US-20080200717-A1 | Process For Producing Ethers | WARNER-LAMBERT COMPANY LLC (US) | 2008-08-21 | — | — | US | claimed |
| EP-1896397-A1 | PROCESS FOR PRODUCING ETHERS | WARNER-LAMBERT COMPANY LLC (US) | 2008-03-12 | — | — | EP | claimed |
| EP-1805206-A2 | ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE | Combimatrix Corporation (US) | 2007-07-11 | — | — | EP | claimed |
| WO-2006136910-A1 | PROCESS FOR PRODUCING ETHERS | WARNER-LAMBERT COMPANY LLC (US) | 2006-12-28 | — | — | WO | claimed |
| US-20060216828-A1 | Rapid-response reversible dry surface CO2 detector | MERCURY ENTERPRISE, INC. | 2006-09-28 | — | — | US | claimed |
| WO-2006031814-A2 | ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE | COMBIMATRIX CORPORATION (US) | 2006-03-23 | — | — | WO | claimed |
| US-20060054511-A1 | Electrochemical deblocking using a hydrazine derivative | CUSTOMARRAY, INC. | 2006-03-16 | — | — | US | claimed |
| US-4217442-A | Polymerization of 2-pyrrolidone with alkali metal pyrrolidonates and certain quaternary ammonium salts | BARNES ARTHUR C (US) | 1980-08-12 | — | — | US | claimed |
| WO-1979000971-A1 | POLYMERIZATION OF 2-PYRROLIDONE | BARNES C (US) | 1979-11-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142699-A1 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM | OPRD1, POLL, OPRM1 | MEN1 4065/4885KMT2A 677/4885LMNA 2408/4885 |
| US-20080200717-A1 | Process For Producing Ethers | CYP3A4, UGT1A4, CYP4B1 | MEN1 1682/4885KMT2A 750/4885LMNA 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.