Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394645 | 0.87 | RAB9A (0.54) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3397250 | 0.79 | RAB9A (0.61) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3394845 | 0.78 | MEN1 (0.57) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3391621 | 0.78 | MAPK14 (0.55) | MEN1KMT2ARAB9ASMN1; SMN2GAA | |
| SCHEMBL3398555 | 0.77 | RAB9A (0.55) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3398516 | 0.77 | RAB9A (0.58) | MEN1KMT2ARAB9ASMN1; SMN2RXFP1 | |
| SCHEMBL2367620 | 0.76 | MAPT (0.81) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL3392231 | 0.74 | MEN1 (0.55) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3390828 | 0.74 | MEN1 (0.56) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3392255 | 0.73 | SMN1; SMN2 (0.53) | MEN1KMT2ARAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | MEN1 3798/4885KMT2A 831/4885RAB9A 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.