Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393541 | 0.90 | CACNA1B (0.56) | RAB9ASMN1; SMN2NPC1AGERTDP1 | |
| SCHEMBL3397270 | 0.89 | PTPN11 (0.50) | RAB9ANPC1AGERP4HTMKMT2A | |
| SCHEMBL3398551 | 0.89 | POLB (0.49) | RAB9ASMN1; SMN2NPC1AGERTDP1 | |
| SCHEMBL3393588 | 0.87 | CSNK2A2 (0.55) | RAB9ASMN1; SMN2NPC1P4HTMKMT2A | |
| SCHEMBL3393963 | 0.84 | NAMPT (0.56) | RAB9ASMN1; SMN2NPC1TDP1NAMPT | |
| SCHEMBL3392231 | 0.82 | MEN1 (0.55) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL3397155 | 0.80 | CSNK2A2 (0.60) | RAB9ASMN1; SMN2NPC1TDP1P4HTM | |
| SCHEMBL3394845 | 0.79 | MEN1 (0.57) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL3391621 | 0.79 | MAPK14 (0.55) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL3397250 | 0.77 | RAB9A (0.61) | RAB9ASMN1; SMN2NPC1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | RAB9A 1982/4885SMN1; SMN2 2662/4885NPC1 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.