SCHEMBL33926

SCHEMBL33926

Nc1ccc(O)c(CO)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.59
ACHE P22303 3/20 0.57
KLF10 Q13118 1/20 0.50
PKM P14618 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
PDE10A Q9Y233 1/20 0.48
CASP1 P29466 2/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 2/20 0.43
HIF1A Q16665 2/20 0.43
MEN1 O00255 1/20 0.43
TNF P01375 1/20 0.43
HSPD1 P10809 1/20 0.43
THRB P10828 1/20 0.43
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10413744 0.98 ACHE (0.60) PRKCIACHEKLF10PKMCA1
SCHEMBL6152960 0.85 PRKCI (0.50) PRKCIACHEKLF10PKMCA1
SCHEMBL30597925 0.83 PRKCI (0.61) PRKCIACHECA1CA2PDE10A
SCHEMBL29358019 0.83 PRKCI (0.61) PRKCIACHECA1CA2PDE10A
SCHEMBL111004 0.83 PRKCI (0.61) PRKCIACHECA1CA2PDE10A
SCHEMBL9763245 0.82 PDE10A (0.52) PRKCIACHEKLF10PKMCA1
SCHEMBL146272 0.82 PRKCI (0.55) PRKCIACHECA1CA2PDE10A
SCHEMBL3164395 0.81 PRKCI (0.46) PRKCIACHEKLF10PKMCA1
Hydrochloric Acid SCHEMBL3337180 0.81 ACHE (0.62) PRKCIACHECA1CA2PDE10A
SCHEMBL15993786 0.81 PRKCI (0.59) PRKCIACHECA1CA2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6790 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118197680-B Power cable 河北飞驰线缆有限公司 2025-02-28 CN claimed
CN-118197680-A Power cable 河北飞驰线缆有限公司 2024-06-14 CN claimed
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20200392088-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-17 US claimed
EP-3464247-B1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES OREAL (FR) 2020-03-11 EP claimed
EP-3464247-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'Oréal (FR) 2019-04-10 EP claimed
WO-2017202884-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2017-11-30 WO claimed
EP-1870084-B1 Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol ORÉAL L (FR) 2015-07-22 EP claimed
EP-0850636-B2 Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition OREAL (FR) 2013-11-20 EP claimed
CN-101444460-B Oxidation dye composition, oxidation dyeing process and use OU LAIYA 2013-08-14 CN claimed
US-4891045-A DYEING HAIR L'OREAL (FR) 1990-01-02 US claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed
EP-0294669-A1 Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair L'OREAL (FR) 1988-12-14 EP claimed
EP-0182187-A1 Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols Wella Aktiengesellschaft (DE) 1986-05-28 EP claimed
WO-1986002829-A1 OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1986-05-22 WO claimed
US-4298673-A CONTAINING AN AMINE; SHARP TOE-GRADATION FUJI PHOTO FILM CO., LTD. (JP) 1981-11-03 US claimed
US-4147543-A Developer compositions for high contrast diffusion transfer photographic materials and process therefor FUJI PHOTO FILM CO., LTD. (JP) 1979-04-03 US claimed