Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.87 |
| ▸ | CASP6 | P55212 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441296 | 0.93 | LMNA (1.00) | LMNACASP6TSHRHCAR3MEN1 | |
| SCHEMBL1162258 | 0.93 | LMNA (1.00) | LMNACASP6TSHRHCAR3MEN1 | |
| SCHEMBL865237 | 0.88 | LMNA (0.65) | LMNACASP6TSHRHCAR3MAPT | |
| 1,5-Pentanediol SCHEMBL8846459 | 0.83 | LMNA (0.79) | LMNACASP6TSHRHCAR3MEN1 | |
| SCHEMBL4632273 | 0.83 | LMNA (0.64) | LMNACASP6TSHRHCAR3MAPT | |
| SCHEMBL27717235 | 0.82 | LMNA (0.71) | LMNACASP6TSHRHCAR3MEN1 | |
| SCHEMBL3392678 | 0.81 | LMNA (0.62) | LMNATSHRMEN1MAPTKMT2A | |
| SCHEMBL31174170 | 0.81 | LMNA (0.77) | LMNACASP6TSHRMEN1MAPT | |
| SCHEMBL865520 | 0.81 | LMNA (0.77) | LMNACASP6TSHRMEN1MAPT | |
| SCHEMBL1607853 | 0.80 | LMNA (0.74) | LMNACASP6TSHRHCAR3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152660-A2 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | Rolic AG (CH) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008145225-A2 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | ROLIC AG (CH) | 2008-12-04 | — | — | WO | disclosed |