1,5-Pentanediol

1,5-Pentanediol

SCHEMBL8846459

Nc1ccc(C(=O)O)cc1[N+](=O)[O-].OCCCCCO

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.79
CASP6 P55212 1/20 0.57
TSHR P16473 2/20 0.53
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HCAR3 P49019 6/20 0.49
MAPT P10636 3/20 0.49
APEX1 P27695 1/20 0.49
TDP1 Q9NUW8 3/20 0.47
POLB P06746 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441296 0.89 LMNA (1.00) LMNACASP6TSHRMEN1KMT2A
SCHEMBL1162258 0.89 LMNA (1.00) LMNACASP6TSHRMEN1KMT2A
1,4-Butanediol SCHEMBL8846548 0.87 LMNA (0.62) LMNACASP6TSHRHCAR3APEX1
SCHEMBL3392676 0.83 LMNA (0.87) LMNACASP6TSHRMEN1KMT2A
SCHEMBL7402680 0.81 CASP6 (0.58) LMNACASP6TSHRHCAR3APEX1
SCHEMBL18109929 0.78 MAPT (0.52) LMNATSHRMEN1KMT2AMAPT
SCHEMBL865520 0.77 LMNA (0.77) LMNACASP6TSHRMEN1KMT2A
SCHEMBL31174170 0.77 LMNA (0.77) LMNACASP6TSHRMEN1KMT2A
SCHEMBL1607853 0.76 LMNA (0.74) LMNACASP6TSHRHCAR3APEX1
SCHEMBL1470130 0.76 LMNA (0.74) LMNACASP6TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0437821-B1 Method for producing polyimide foam products. IMI TECH CORP (US) 1997-07-30 EP disclosed
EP-0351544-B1 Production of foamed polymer structures ALBEMARLE CORP (US) 1994-10-05 EP disclosed
EP-0349796-B1 Production of foamed polymer structures ETHYL CORP (US) 1994-09-21 EP disclosed
EP-0348722-B1 Production of foamed polymer structures ETHYL CORP (US) 1994-08-17 EP disclosed
US-5234966-A Adding to precursor polar protic foam-enhancing additive ETHYL CORPORATION (US) 1993-08-10 US disclosed
US-5122546-A Slurry of equimolar amounts of lower alkyl diester of tetracarboxylic acid, diamine, and volatile polar protic foam enhancing additive ETHYL CORPORATION (US) 1992-06-16 US disclosed
US-5096932-A Adding polar, protic foaming agent to aromatic diamine and tetracarboxylic acid ester; slurrying, curing ETHYL CORPORATION (US) 1992-03-17 US disclosed
US-5077318-A Adding a foam-enhancing polar protic alcohol or water to the polyimide melt ETHYL CORPORATION (US) 1991-12-31 US disclosed
US-5064867-A Microwaves, Compression ETHYL CORPORATION (US) 1991-11-12 US disclosed
EP-0437821-A2 Polyimide foam products and methods Imi-Tech Corporation (US) 1991-07-24 EP disclosed
US-4874452-A SUBJECTING CURED POLYIMIDE FOAM TO PRESSURIZED STEAM IMI-TECH CORPORATION (US) 1989-10-17 US disclosed
US-4866104-A FLEXIBILITY, SOFTNESS ETHYL CORPORATION (US) 1989-09-12 US disclosed
US-4855331-A FOAMING BY MICROWAVE RADIATION UNDER A VAPOR IMPERMIABLE SHIEL D ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4855332-A 2-/VICINAL-DICARBOXYCYCLOHEXENYUL/SUCCINIC ACID ETHYL CORPORATION (US) 1989-08-08 US disclosed
US-4839398-A FLEXIBILITY, COMPRESSIVE STRENGTH, AGING RESISTANCE ETHYL CORPORATION (US) 1989-06-13 US disclosed
US-4826886-A AIRCRAFT SEAT CUSHIONS ETHYL CORPORATION (US) 1989-05-02 US disclosed
US-4822537-A MICROWAVE IRRADIATION OF POLYIMIDE ETHYL CORPORATION (US) 1989-04-18 US disclosed
US-4816493-A TETRACARBOXYLIC ACID, AMINOAROMATIC ACID, ESTER OF DIOL ETHYL CORPORATION (US) 1989-03-28 US disclosed
US-4814357-A Polyimide foams and their preparation ETHYL CORPORATION (US) 1989-03-21 US disclosed
US-4804504-A MICROWAVE RADIATION OF POLYIMIDE PRECURSOR UNDER VAPOR IMPERMEABLE COVERING ETHYL CORPORATION (US) 1989-02-14 US disclosed