Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392810 | 1.00 | KMT2A (0.32) | KMT2AFLT3MAPK1CHRM2GRM5 | |
| SCHEMBL5223201 | 0.82 | NOS3 (0.38) | KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL17395190 | 0.82 | NOS3 (0.38) | KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL2760746 | 0.79 | KMT2A (0.50) | KMT2ACHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL28286419 | 0.78 | PRMT1 (0.41) | KMT2ACHRM2GRM5SIGMAR1 | |
| SCHEMBL14153307 | 0.77 | GRM5 (0.51) | FLT3CHRM2GRM5SIGMAR1 | |
| SCHEMBL14993380 | 0.73 | ADRA2A (0.47) | KMT2AMAPK1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL13783338 | 0.73 | KDM1A (0.40) | KMT2AMAPK1RAB9ANPC1MITF | |
| SCHEMBL18547170 | 0.73 | P4HTM (0.55) | KMT2AMAPK1PKMKDM4EL3MBTL1 | |
| SCHEMBL17394925 | 0.73 | KDM1A (0.40) | KMT2AMAPK1RAB9ANPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-09-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | HTRA1, PRSS1, PRNP | KMT2A 4400/4885FLT3 1963/4885MAPK1 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.