Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | KIF11 | P52732 | 3/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethylbenzene SCHEMBL11020953 | 0.98 | TSHR (0.67) | TSHRALDH1A1KIF11TAAR1TRPV6 | |
| Trifluoromethylbenzene SCHEMBL11580827 | 0.87 | TSHR (0.82) | TSHRALDH1A1KIF11TAAR1TRPV6 | |
| Trifluoromethylbenzene SCHEMBL14891620 | 0.85 | ALDH1A1 (0.70) | TSHRALDH1A1KIF11TRPV6KCNN4 | |
| Trifluoromethylbenzene SCHEMBL27877750 | 0.84 | ALDH1A1 (0.61) | TSHRALDH1A1KIF11TAAR1SLC6A2 | |
| Trifluoromethylbenzene SCHEMBL21879063 | 0.84 | TSHR (0.88) | TSHRALDH1A1KIF11TRPV6KCNN4 | |
| Trifluoromethylbenzene SCHEMBL4867878 | 0.84 | TSHR (0.88) | TSHRALDH1A1KIF11TRPV6KCNN4 | |
| Trifluoromethylbenzene SCHEMBL28143223 | 0.84 | TSHR (0.88) | TSHRALDH1A1KIF11TAAR1TRPV6 | |
| Trifluoromethylbenzene SCHEMBL175647 | 0.84 | TSHR (1.00) | TSHRALDH1A1KIF11TRPV6KCNN4 | |
| Trifluoromethylbenzene SCHEMBL8692 | 0.84 | TSHR (1.00) | TSHRALDH1A1KIF11TRPV6KCNN4 | |
| Trifluoromethylbenzene SCHEMBL27760126 | 0.84 | TSHR (1.00) | TSHRALDH1A1KIF11TRPV6KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184986-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING CHRONIC PAIN AND PAIN ASSOCIATED WITH NEUROPATHY | Trinity Laboratories, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009021058-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING CHRONIC PAIN AND PAIN ASSOCIATED WITH NEUROPATHY | TRINITY LABORTORIES, INC. (US) | 2009-02-12 | — | — | WO | disclosed |
| US-4307755-A | Glass fiber reinforced synthetic resin tube having integral metal attachment | A. B. CHANCE COMPANY (US) | 1981-12-29 | — | — | US | disclosed |