⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230434 | 0.89 | ALDH1A1 (0.39) | — | |
| SCHEMBL1230432 | 0.89 | ALDH1A1 (0.39) | — | |
| SCHEMBL7171718 | 0.87 | ALDH1A1 (0.38) | — | |
| SCHEMBL7171712 | 0.87 | ALDH1A1 (0.38) | — | |
| SCHEMBL42869 | 0.86 | — | — | |
| SCHEMBL16136558 | 0.86 | — | — | |
| SCHEMBL387010 | 0.81 | — | — | |
| SCHEMBL17656188 | 0.78 | ADH1A (0.32) | — | |
| SCHEMBL17656185 | 0.78 | ADH1A (0.32) | — | |
| SCHEMBL20542564 | 0.78 | ADH1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191620-A | A kind of method that amitriptyline intermediate is prepared using solid acid catalyst | 河南中医药大学 | 2018-06-22 | — | — | CN | claimed |
| CN-105218405-B | The synthesis technique of (R, S) 2 [[base of 5 (9 fluorenylmethyloxycarbonyl amino) dibenzo [A, D] cycloheptane 2] oxygen] acetic acid | 上海泰坦科技股份有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-102892492-A | Delivery particle | PROCTER & GAMBLE | 2013-01-23 | — | — | CN | claimed |
| CN-110300753-A | Cap dependence endonuclease enzyme inhibitor | 太景生物科技股份有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-110088100-A | Pyrimidone derivatives as CDC7 inhibitor | 癌症研究科技有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110036006-A | The preparation and use of pyrimidone derivatives | 癌症研究科技有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109535134-A | compound and organic electronic device using the same | 彩丰精技股份有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-109336772-A | A kind of triaromatic amine compound containing spiro structure and application thereof and luminescent device | 上海道亦化工科技有限公司 | 2019-02-15 | — | — | CN | disclosed |
| CN-108794535-A | Iridium complex of cyclic quinoxaline fused ligand and organic light emitting diode assembly | 杰秀有限公司 | 2018-11-13 | — | — | CN | disclosed |
| CN-108586251-A | A kind of preparation method of benzoyl contraposition fluoroalkyl derivative | 苏州大学 | 2018-09-28 | — | — | CN | disclosed |
| EP-2391597-B1 | METHOD FOR PRODUCING PURE CYCLODODECANONE | BASF SE (DE) | 2018-08-22 | — | — | EP | disclosed |
| WO-2000004011-A1 | CYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DYSLIPIDAEMIA, ATHEROSCLEROSIS AND DIABETES, PHARMACEUTICAL COMPOSITIONS AND PREPARATION PROCESS | MERCK PATENT GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |
| CN-1047774-C | Prepn of azadiphenyl cycloheptyl ketenes | HUALIAN PHARMACEUTICAL CO SHAN (CN) | 1999-12-29 | — | — | CN | disclosed |
| CN-1235826-A | 10, 11 methanodibenzosuberane derivatives used as chemosensitizing agents | SYNTEX INC (US) | 1999-11-24 | — | — | CN | disclosed |
| CN-1204258-A | Novel method | NOVO NORDISK AS (DK) | 1999-01-06 | — | — | CN | disclosed |
| US-5767120-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS; TREATMENT FOR SEPTIC SHOCK | SCHERING CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |
| CN-1142183-A | A method of treating neurogenic inflammation | NOVO NORDISK AS (DK) | 1997-02-05 | — | — | CN | disclosed |
| EP-0735872-A1 | A METHOD OF TREATING NEUROGENIC INFLAMMATION | NOVO NORDISK A/S (DK) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995018615-A1 | A METHOD OF TREATING NEUROGENIC INFLAMMATION | NOVO NORDISK A/S (DK) | 1995-07-13 | — | — | WO | disclosed |
| US-4142051-A | Arylaminoimidazoline derivatives | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1979-02-27 | — | — | US | disclosed |