Urea

Urea

SCHEMBL3393016

C=C(CCO)CCO.NC(N)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
OR51E2 Q9H255 1/20 0.38
CAMK2A Q9UQM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070929 0.83
Ammonia Solution, Strong SCHEMBL2637991 0.79 TSHR (0.31)
SCHEMBL35589 0.79
SCHEMBL30888177 0.77
Urea SCHEMBL29140399 0.75 GRIK1 (0.39) TDP1ALDH1A1LMNAOR51E2CAMK2A
SCHEMBL11439577 0.73
Urea SCHEMBL133649 0.73 TDP1 (0.43) TDP1ALDH1A1LMNAOR51E2
Urea SCHEMBL9579182 0.73 CES2 (0.45) TDP1ALDH1A1LMNAOR51E2
SCHEMBL23668543 0.73 SLC22A6 (0.55) TDP1ALDH1A1LMNACAMK2A
SCHEMBL9773632 0.73 TDP1 (0.33) TDP1ALDH1A1LMNAOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9976055-B2 Lower temperature cure coating compositions KING INDUSTRIES (US) 2018-05-22 US disclosed
EP-3114164-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS King Industries, Inc. (US) 2017-01-11 EP disclosed
US-20150197665-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES (US) 2015-07-16 US disclosed
WO-2015106174-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES (US) 2015-07-16 WO disclosed
US-20130216723-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2013-08-22 US disclosed
US-8431730-B2 Sulfonate esters as latent acid catalysts KING INDUSTRIES (US) 2013-04-30 US disclosed
EP-2203519-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS King Industries (US) 2010-07-07 EP disclosed
US-20090104363-A1 Sulfonate esters as latent acid catalysts KING INDUSTRIES 2009-04-23 US disclosed
WO-2009045466-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2009-04-09 WO disclosed
EP-0082832-B1 RADIATION AND HEAT CURABLE COMPOSITIONS COMPRISING ISOCYANURIC ACID-ACROLEIN DERIVATIVES MONSANTO COMPANY (US) 1986-02-26 EP disclosed
US-4477618-A CROSSLINKING AN ACTIVE HYDROGEN-CONTAINING RESIN BLEND BY BAKING; STORAGE STABILITY PPG INDUSTRIES, INC. (US) 1984-10-16 US disclosed
US-4469832-A SPRAYABLE COATINGS PPG INDUSTRIES, INC. (US) 1984-09-04 US disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed
US-4447594-A Heat-curable compositions comprising isocyanuric acid-acrolein derivatives MONSANTO COMPANY (US) 1984-05-08 US disclosed
US-4417022-A SOLVENT-FREE PPG INDUSTRIES, INC. (US) 1983-11-22 US disclosed
EP-0082832-A2 Radiation and heat curable compositions comprising isocyanuric acid-acrolein derivatives MONSANTO COMPANY (US) 1983-06-29 EP disclosed
US-4343925-A POLYESTERS PPG INDUSTRIES, INC. (US) 1982-08-10 US disclosed
US-4317894-A Low temperature cure coating compositions PPG INDUSTRIES, INC. (US) 1982-03-02 US disclosed
US-4314918-A Coating compositions containing organic alcoholic reactive diluents PPG INDUSTRIES, INC. (US) 1982-02-09 US disclosed
US-3959201-A High solids, water thinnable compositions PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104363-A1 Sulfonate esters as latent acid catalysts ORAI1, SARAF, NAPA TDP1 3978/4885ALDH1A1 3647/4885LMNA 306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.