Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28851924 | 0.80 | ERN1 (0.36) | CA2ALDH1A1CYP3A4POLBL3MBTL1 | |
| SCHEMBL27695180 | 0.78 | TRPV4 (0.36) | ALDH1A1CYP3A4POLBL3MBTL1MAPT | |
| SCHEMBL1810937 | 0.76 | CA12 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL743497 | 0.76 | CA12 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2235124 | 0.74 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2164088 | 0.74 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2164186 | 0.74 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27755946 | 0.74 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8860398 | 0.71 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29178171 | 0.71 | CA1 (0.39) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209841-B | Synthesis method of terbutaline and application of terbutaline in preparation of terbutaline sulfate | 扬州中宝药业股份有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-112209841-A | Synthesis method of terbutaline and application of terbutaline in preparation of terbutaline sulfate | 扬州中宝药业股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-101402623-A | 3-substituted benzene phthalein compounds with biological activity | SHANGHAI INST ORGANIC CHEM (CN) | 2009-04-08 | — | — | CN | claimed |
| EP-3636636-B1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | MITSUI CHEMICALS AGRO INC (JP) | 2022-07-06 | — | — | EP | disclosed |
| CN-112209841-B | Synthesis method of terbutaline and application of terbutaline in preparation of terbutaline sulfate | 扬州中宝药业股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-112209841-B | Synthesis method of terbutaline and application of terbutaline in preparation of terbutaline sulfate | 扬州中宝药业股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-09-14 | — | — | US | disclosed |
| CN-112209841-A | Synthesis method of terbutaline and application of terbutaline in preparation of terbutaline sulfate | 扬州中宝药业股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-112209841-A | Synthesis method of terbutaline and application of terbutaline in preparation of terbutaline sulfate | 扬州中宝药业股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-107635981-B | Compounds and methods for inducing browning of white adipose tissue | 中国科学院广州生物医药与健康研究院 | 2020-08-04 | — | — | CN | disclosed |
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-3636636-A1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | Mitsui Chemicals Agro, Inc. (JP) | 2020-04-15 | — | — | EP | disclosed |
| CN-103189383-B | Biaryl diphosphine ligand, its intermediate and the purposes in asymmetry catalysis thereof | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2016-11-30 | — | — | CN | disclosed |
| CN-103189383-A | Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis | KANATA CHEMICAL TECHNOLOGIES INC | 2013-07-03 | — | — | CN | disclosed |
| EP-2145888-A1 | Deazapurine derivatives as HSP90-Inhibitors | Conforma Therapeutics Corporation (US) | 2010-01-20 | — | — | EP | disclosed |
| CN-101402623-A | 3-substituted benzene phthalein compounds with biological activity | SHANGHAI INST ORGANIC CHEM (CN) | 2009-04-08 | — | — | CN | disclosed |
| US-20070185064-A1 | 2-Aminopurine Analogs Having HSP90-Inhibiting Activity | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| US-7138401-B2 | 2-aminopurine analogs having HSP90-inhibiting activity | CONFORMA THERAPEUTICS CORPORATION (US) | 2006-11-21 | — | — | US | disclosed |
| US-20050113340-A1 | 2-Aminopurine analogs having HSP90-inhibiting activity | CONFORMA THERAPEUTICS CORPORATION | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CBR3, CBR1 | CA12 4431/4885CA1 2325/4885CA2 986/4885 |
| US-20050113340-A1 | 2-Aminopurine analogs having HSP90-inhibiting activity | HSP90AB2P, HSP90AB1, HSP90AA1 | CA12 4540/4885CA1 4219/4885CA2 4096/4885 |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CBR3, CBR1 | CA12 4431/4885CA1 2325/4885CA2 986/4885 |
| US-20070185064-A1 | 2-Aminopurine Analogs Having HSP90-Inhibiting Activity | HSP90AB2P, HSP90AB1, HSP90AA1 | CA12 4540/4885CA1 4219/4885CA2 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.