Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389021 | 0.95 | KCNH2 (0.44) | KCNH2TDP1L3MBTL1DHFRTLR8 | |
| SCHEMBL3388204 | 0.93 | KCNH2 (0.47) | KCNH2TDP1L3MBTL1DHFRGPR84 | |
| SCHEMBL1944627 | 0.89 | KCNH2 (0.32) | KCNH2TDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL3389193 | 0.82 | CCR1 (0.37) | TDP1L3MBTL1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3803910 | 0.80 | TP53 (0.49) | TDP1L3MBTL1SMN1; SMN2NPC1MAPT | |
| SCHEMBL27883130 | 0.79 | TP53 (0.47) | KCNH2TDP1SMN1; SMN2NPC1MAPT | |
| SCHEMBL3391256 | 0.74 | CCR1 (0.52) | NOS2MAPTTGFBR1 | |
| SCHEMBL3389939 | 0.70 | TRPM8 (0.41) | GABRA1GABRB2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1948200 | 0.68 | KDM4E (0.34) | GABRA1GABRB2TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2506412 | 0.68 | KDM4E (0.34) | GABRA1GABRB2TDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | claimed |
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-30 | — | — | US | claimed |
| CN-102614683-B | Method for separating element palladium and sub-actinide elements from high-level waste | UNIV ZHEJIANG | 2014-01-15 | — | — | CN | disclosed |
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | CBR3, CBR1, TH | KCNH2 209/4885GABRP 2072/4885GABRD 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.