Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389193 | 0.76 | CCR1 (0.37) | KDM4EHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL1944627 | 0.73 | KCNH2 (0.32) | KDM4EHPGDALDH1A1CTSSCTSK | |
| SCHEMBL3393079 | 0.70 | KCNH2 (0.38) | HPGDGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2506412 | 0.69 | KDM4E (0.34) | KDM4EGABRA1GABRB2SMN1; SMN2 | |
| SCHEMBL1948200 | 0.69 | KDM4E (0.34) | KDM4EGABRA1GABRB2SMN1; SMN2 | |
| SCHEMBL3389652 | 0.68 | GPR84 (0.35) | KDM4EIDH1IDH2SMN1; SMN2 | |
| SCHEMBL3391256 | 0.68 | CCR1 (0.52) | IDH1 | |
| SCHEMBL17971497 | 0.66 | MAPT (0.46) | TRPM8KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL3388222 | 0.65 | CCR1 (0.41) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL15058689 | 0.63 | TRPM8 (0.38) | TRPM8KDM4EHPGDUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | claimed |
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-30 | — | — | US | claimed |
| CN-102614683-B | Method for separating element palladium and sub-actinide elements from high-level waste | UNIV ZHEJIANG | 2014-01-15 | — | — | CN | disclosed |
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | CBR3, CBR1, TH | TRPM8 4377/4885KDM4E 1789/4885HPGD 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.