Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487163 | 0.80 | CYP2D6 (0.30) | CYP2D6CYP2C19 | |
| SCHEMBL16194339 | 0.75 | DPP4 (0.46) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL18633059 | 0.75 | DPP4 (0.46) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL8529804 | 0.73 | CPN1 (0.40) | CPN1CPB2 | |
| SCHEMBL3102774 | 0.72 | — | — | |
| SCHEMBL16399448 | 0.70 | CPN1 (0.32) | CPN1CPB2 | |
| SCHEMBL9205681 | 0.69 | SLC6A3 (0.41) | LMNATSHRALDH1A1CPN1CPB2 | |
| SCHEMBL12480009 | 0.69 | CYP2C19 (0.37) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL23421119 | 0.68 | CYP2C19 (0.71) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL16620358 | 0.68 | CYP2C19 (0.71) | CYP2D6LMNABLMALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046713-A2 | METHODS FOR PREPARING HETEROCYCLIC RINGS | ISIS INNOVATION (GB) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046713-A2 | METHODS FOR PREPARING HETEROCYCLIC RINGS | ISIS INNOVATION (GB) | 2010-04-29 | — | — | WO | disclosed |