Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 3/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205681 | 0.90 | SLC6A3 (0.41) | CPN1CPB2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3102774 | 0.83 | — | — | |
| SCHEMBL3986419 | 0.81 | CPN1 (0.39) | CPN1CPB2CPA1 | |
| SCHEMBL11502339 | 0.81 | CPN1 (0.41) | CPN1CPB2SLC1A2 | |
| SCHEMBL16399448 | 0.80 | CPN1 (0.32) | CPN1CPB2 | |
| SCHEMBL23730597 | 0.79 | CPN1 (0.58) | CPN1CPB2SLC1A2 | |
| SCHEMBL5797547 | 0.78 | CPN1 (0.31) | CPN1CPB2 | |
| SCHEMBL1775857 | 0.73 | CPN1 (0.67) | CPN1CPB2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4983949 | 0.73 | SLC6A3 (0.38) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3393111 | 0.73 | CYP2D6 (0.35) | CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504612-B1 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID CO (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5700930-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| CN-1166489-A | Prep. of novel alkyl-substituted alpha-ketone ester | AMERICAN CYANAMID CO (US) | 1997-12-03 | — | — | CN | disclosed |
| US-5656753-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5371215-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5189158-A | 4-SUBSTITUTED AZETIDINONES AS PRECURSORS TO 2-SUBSTITUTED-3-CARBOXY CARBAPENEM ANTIBIOTICS AND A METHOD OF PRODUCING THEM | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| CN-1065061-A | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxycarbapenem antibiotics and processes for their preparation | AMERICAN CYANAMID CO (US) | 1992-10-07 | — | — | CN | disclosed |
| EP-0504612-A2 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1992-09-23 | — | — | EP | disclosed |