SCHEMBL3393153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3394453	0.88	SLC6A4 (0.42)	CACNA2D1CACNA1BCACNB1CACNA1CCHRM4
	SCHEMBL3394232	0.88	CACNA2D1 (0.52)	CACNA2D1CACNA1BCACNB1CACNA1CCHRM3
	SCHEMBL3394123	0.85	CACNA2D1 (0.54)	CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1
	SCHEMBL3392822	0.83	CACNA2D1 (0.41)	CACNA2D1CACNA1BCACNB1CACNA1CKMT2A
	SCHEMBL3390184	0.77	SLC6A4 (0.53)	CHRM4CHRM3SLC6A4SLC6A3
	SCHEMBL2844526	0.76	MAPT (0.53)	—
	SCHEMBL2794508	0.74	LMNA (0.43)	CACNA2D1CACNA1BCACNB1CACNA1CCHRM4
	SCHEMBL3391274	0.72	CACNA2D1 (0.53)	CACNA2D1CACNA1BCACNB1CACNA1CSLC6A4
	SCHEMBL3394200	0.71	CACNA2D1 (0.67)	CACNA2D1CACNA1BCACNB1CACNA1CCHRM3
	SCHEMBL19112558	0.71	SLC6A4 (0.56)	SLC6A4SLC6A3CCR5SLC6A9SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.