Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.34 |
| ▸ | CDK11A | Q9UQ88 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392100 | 0.93 | PTK2B (0.39) | PTK2BMAPK14LMNATSHRALOX12 | |
| SCHEMBL3393224 | 0.93 | GBA1 (0.38) | PTK2BMAPK14LMNATSHRALOX12 | |
| SCHEMBL3174404 | 0.92 | MAPK14 (0.38) | PTK2BMAPK14LMNATSHRMAPK13 | |
| SCHEMBL3392554 | 0.91 | PTK2B (0.37) | PTK2BMAPK14TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL3394251 | 0.90 | PTK2B (0.39) | PTK2BMAPK14LMNATSHRKDM4E | |
| SCHEMBL3394297 | 0.90 | PTK2B (0.40) | PTK2BMAPK14LMNAMAPK13MAPK12 | |
| SCHEMBL3392562 | 0.88 | KMT2A (0.36) | PTK2BMAPK14TSHRMAPK13MAPK12 | |
| SCHEMBL3180430 | 0.88 | CDK8 (0.35) | PTK2BMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3393200 | 0.88 | PTK2B (0.37) | PTK2BMAPK14LMNAMAPK13MAPK12 | |
| SCHEMBL3422290 | 0.87 | MAPK14 (0.37) | PTK2BMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943243-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2010-12-29 | — | — | EP | disclosed |