Carbazole

Carbazole

SCHEMBL3393214

NC(CS)C(=O)O.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.53
SLC7A11 Q9UPY5 1/20 0.53
KDM4E B2RXH2 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
LMNA P02545 1/20 0.51
MPO P05164 1/20 0.51
MAPT P10636 1/20 0.51
TSHR P16473 1/20 0.51
BLM P54132 1/20 0.51
PMP22 Q01453 1/20 0.51
HIF1A Q16665 1/20 0.51
ALDH1A1 P00352 2/20 0.47
GPR3 P46089 1/20 0.47
HSD17B10 Q99714 1/20 0.47
FOLH1 Q04609 1/20 0.45
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
XIAP P98170 1/20 0.44
SLC7A5 Q01650 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbazole SCHEMBL450294 1.00 PTGS1 (0.53) PTGS1SLC7A11KDM4EMEN1KMT2A
Carbazole SCHEMBL28207216 0.98 PTGS1 (0.52) PTGS1SLC7A11KDM4EMEN1KMT2A
Carbazole SCHEMBL738564 0.94 PTGS1 (0.47) PTGS1SLC7A11KDM4EMEN1KMT2A
Carbazole SCHEMBL7710915 0.94 PTGS1 (0.47) PTGS1SLC7A11KDM4EMEN1KMT2A
Phenanthrene SCHEMBL28220628 0.79 PTGS1 (0.57) PTGS1SLC7A11KDM4EMEN1KMT2A
Cysteine SCHEMBL5818761 0.79 PTGS1 (0.57) PTGS1SLC7A11KDM4EMEN1KMT2A
Carbazole SCHEMBL2935661 0.79 ALDH1A1 (0.54) KDM4EMEN1KMT2ALMNAALDH1A1
Carbazole SCHEMBL2935659 0.79 ALDH1A1 (0.54) KDM4EMEN1KMT2ALMNAALDH1A1
Carbazole SCHEMBL9985926 0.78 GSR (0.59) KDM4EMEN1KMT2ALMNAMPO
Biphenyl SCHEMBL27974455 0.78 PTGS1 (0.67) PTGS1SLC7A11FOLH1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10014598-A None JP disclosed
CN-118207235-A Genetically engineered bacterium for recombinant expression of L-arabinose isomerase and construction method and application thereof 广东海洋大学 2024-06-18 CN disclosed
US-20240002828-A1 NOVEL L-RHAMNOSE ISOMERASE NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY (JP) 2024-01-04 US disclosed
EP-4257687-A1 NOVEL L-RHAMNOSE ISOMERASE National University Corporation Kagawa University (JP) 2023-10-11 EP disclosed
CN-116783300-A Novel L-rhamnose isomerase 国立大学法人香川大学 2023-09-19 CN disclosed
CN-110951717-B L-arabinose isomerase isomer and application thereof 浙江工业大学 2023-08-18 CN disclosed
CN-116496942-A Strain for producing D-tagatose and application thereof 南京工业大学 2023-07-28 CN disclosed
CN-111057697-B High-temperature-resistant TIM barrel protein mutant and application thereof 浙江工业大学 2023-03-31 CN disclosed
CN-110904088-B High-temperature-resistant D-psicose3-epimerase, mutant and application thereof 浙江工业大学 2023-03-28 CN disclosed
EP-4130278-A1 NOVEL L-RHAMNOSE ISOMERASE National University Corporation Kagawa University (JP) 2023-02-08 EP disclosed
US-6057135-A PREPARING MONOSACCHARIDE FROM CHEESE WHEY, MILK, OR CHEESE WHEY AND MILK; FILTERING CHEESE WHEY OR MILK TO MAKE LACTOSE, HYDROLYZE TO GLUCOSE AND GALACTOSE, FERMENT TO ETHANOL, SEPARATING GALACTOSE, ISOMERIZE GALACTOSE TO MONOSACCHARIDE KRAFT FOODS, INC. (US) 2000-05-02 US disclosed
JP-H1014598-A MEASUREMENT OF GLUCOSE NONOGAWA SHOJI KK 1998-01-20 JP disclosed
EP-0552894-A2 D-tagatose production by enzymatic isomerization of D-galactose KRAFT FOODS, INC. (US) 1993-07-28 EP disclosed
EP-0097973-B1 PROCESS FOR PREPARING FRUCTOSE NABISCO BRANDS, Inc. (US) 1989-07-12 EP disclosed
US-4605619-A TREATING STARCH WITH ALPHA-AMYLASE, CONTACTING THE PRODUCT WITH GLUCOAMYLASE, AND ISOMERIZING THE RESULTING GLUCOSE TO FRUCTOSE USING GLUCOSE ISOMERASE NABISCO BRANDS, INC. (US) 1986-08-12 US disclosed
US-4458017-A ENZYMATIC LIQUEFACTION, HYDROLYSIS AND ISOMERIZATION NABISCO BRANDS, INC. (US) 1984-07-03 US disclosed
US-4447531-A ISOMERIZING GLUCOSE TO FRUCTOSE NABISCO BRANDS, INC. (US) 1984-05-08 US disclosed
US-4431733-A ENZYMATIC HYDROLYSIS AND ISOMERIZATION; FOOD PROCESSING NABISCO BRANDS, INC. (US) 1984-02-14 US disclosed
EP-0097973-A2 Process for preparing fructose NABISCO BRANDS, Inc. (US) 1984-01-11 EP disclosed
US-3957578-A MOLD OF GENUS ABSIDIA HOKKAIDO SUGAR CO., LTD. (JA) 1976-05-18 US disclosed