SCHEMBL3393221

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3392944	0.87	HTT (0.47)	GPR119HTTJAK2MEN1KMT2A
	SCHEMBL27679141	0.87	CDK2 (0.38)	HDAC3HDAC1HDAC2
	SCHEMBL3994799	0.86	TLR9 (0.38)	GPR119JAK2MEN1KMT2AHDAC3
	SCHEMBL3391862	0.86	GPR119 (0.47)	GPR119HTTJAK2MEN1KMT2A
	SCHEMBL3792007	0.84	IKBKB (0.51)	GPR119
	SCHEMBL3395346	0.83	JAK2 (0.45)	GPR119HTTJAK2MEN1KMT2A
	SCHEMBL3395565	0.83	GPR119 (0.49)	GPR119HTTJAK2GBA1MEN1
	SCHEMBL3391151	0.82	GPR119 (0.48)	GPR119HTTJAK2MEN1KMT2A
	SCHEMBL3394095	0.82	GPR119 (0.47)	GPR119HTTJAK2MEN1KMT2A
	SCHEMBL3392527	0.82	IKBKB (0.52)	CNR1LMNATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.