Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27837801 | 0.80 | EPHX1 (0.50) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL131351 | 0.78 | SLC6A2 (0.54) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL28188881 | 0.77 | CSNK1E (0.45) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL3508191 | 0.73 | LOXL2 (0.43) | EPHX1TAAR1MAOACYP2A6 | |
| SCHEMBL28059528 | 0.73 | MMP2 (0.44) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL28059581 | 0.73 | LOXL2 (0.47) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL1598678 | 0.72 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL4950698 | 0.72 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL1263137 | 0.72 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL2921309 | 0.72 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |