Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.45 |
| ▸ | SHBG | P04278 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069733 | 1.00 | NR3C1 (0.58) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL8201277 | 0.89 | NR3C1 (0.57) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL12265810 | 0.89 | NR3C1 (0.57) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL11702398 | 0.89 | NR3C1 (0.57) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL8201270 | 0.89 | NR3C1 (0.57) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL11702404 | 0.89 | NR3C1 (0.57) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL15144390 | 0.89 | NR3C1 (0.57) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL10412565 | 0.88 | NR3C1 (0.56) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL15147191 | 0.87 | NR3C1 (0.62) | NR3C1LMNAHIF1AMEN1KMT2A | |
| SCHEMBL11703940 | 0.87 | NR3C1 (0.50) | NR3C1LMNAHIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246359-A1 | Process for obtaining fluorometholone and intermediates therefor | Crystal Pharma, S.L.U. (ES) | 2010-11-03 | — | — | EP | disclosed |
| EP-0187847-A1 | PROCESS FOR THE MANUFACTURE OF 6$g(A)-METHYL STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-07-23 | — | — | EP | disclosed |
| WO-1986000907-A1 | PROCESS FOR THE MANUFACTURE OF 6ALPHA-METHYL STEROIDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1986-02-13 | — | — | WO | disclosed |