Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 16/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205267 | 1.00 | MET (0.47) | METHTR2CHTR6HTR2ADRD3 | |
| SCHEMBL3214108 | 1.00 | MET (0.47) | METHTR2CHTR6HTR2ADRD3 | |
| SCHEMBL7946592 | 0.88 | HTR6 (0.45) | HTR2CHTR6KLK7 | |
| SCHEMBL3203927 | 0.85 | HTR6 (0.61) | METHTR2CHTR6DRD3 | |
| SCHEMBL3204063 | 0.85 | HTR6 (0.61) | METHTR2CHTR6DRD3 | |
| SCHEMBL3215266 | 0.85 | HTR6 (0.61) | METHTR2CHTR6DRD3 | |
| SCHEMBL3193410 | 0.80 | HTR6 (0.50) | HTR6 | |
| SCHEMBL3207560 | 0.80 | HTR6 (0.51) | HTR2CHTR6KLK7 | |
| SCHEMBL3209731 | 0.80 | HTR6 (0.51) | HTR2CHTR6KLK7 | |
| SCHEMBL3191687 | 0.80 | HTR6 (0.40) | HTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011546-A2 | ACYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |