Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339675 | 1.00 | LPAR3 (0.37) | LPAR3LPAR1LPAR2P2RY10SGPL1 | |
| SCHEMBL339695 | 1.00 | LPAR3 (0.37) | LPAR3LPAR1LPAR2P2RY10SGPL1 | |
| SCHEMBL5663655 | 0.86 | LPAR3 (0.36) | LPAR3LPAR1LPAR2P2RY10SGPL1 | |
| SCHEMBL5673069 | 0.85 | FABP3 (0.41) | LPAR3S1PR1 | |
| SCHEMBL5672161 | 0.82 | LPAR3 (0.34) | LPAR3LPAR1LPAR2P2RY10S1PR1 | |
| SCHEMBL339933 | 0.80 | CDC25A (0.36) | LPAR3LPAR1LPAR2P2RY10SGPL1 | |
| SCHEMBL340043 | 0.80 | CDC25A (0.36) | LPAR3LPAR1LPAR2P2RY10SGPL1 | |
| SCHEMBL338952 | 0.80 | CDC25A (0.36) | LPAR3LPAR1LPAR2P2RY10SGPL1 | |
| SCHEMBL339734 | 0.79 | LPAR3 (0.32) | LPAR3LPAR1LPAR2P2RY10SGPL1 | |
| SCHEMBL339773 | 0.79 | SIGMAR1 (0.38) | LPAR3LPAR1LPAR2P2RY10SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097752-B2 | Antiprotozoal ring-substituted phospholipids | MAKSCIENTIFIC, LLC (US) | 2012-01-17 | — | — | US | claimed |
| US-8097752-B2 | Antiprotozoal ring-substituted phospholipids | MAKSCIENTIFIC, LLC (US) | 2012-01-17 | — | — | US | disclosed |