Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338887 | 1.00 | SIGMAR1 (0.38) | SIGMAR1LPAR3LPAR1LPAR2S1PR1 | |
| SCHEMBL339695 | 0.79 | LPAR3 (0.37) | LPAR3LPAR1LPAR2S1PR1P2RY10 | |
| SCHEMBL339675 | 0.79 | LPAR3 (0.37) | LPAR3LPAR1LPAR2S1PR1P2RY10 | |
| SCHEMBL339429 | 0.79 | LPAR3 (0.37) | LPAR3LPAR1LPAR2S1PR1P2RY10 | |
| SCHEMBL339730 | 0.79 | SIGMAR1 (0.59) | SIGMAR1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL24103962 | 0.78 | LPAR3 (0.47) | LPAR3LPAR1LPAR2S1PR1S1PR2 | |
| SCHEMBL28586513 | 0.75 | DNM1 (0.54) | LPAR3LPAR1LPAR2S1PR1S1PR2 | |
| SCHEMBL28589099 | 0.75 | DNM1 (0.54) | LPAR3LPAR1LPAR2S1PR1S1PR2 | |
| SCHEMBL17832987 | 0.75 | AKT1 (0.40) | LPAR3LPAR1LPAR2S1PR1S1PR2 | |
| SCHEMBL17817569 | 0.73 | LMNA (0.55) | LPAR3LPAR1LPAR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | MAK SCIENTIFIC CORPORATION (US) | 2006-05-18 | — | — | US | claimed |
| US-8097752-B2 | Antiprotozoal ring-substituted phospholipids | MAKSCIENTIFIC, LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | MAK SCIENTIFIC CORPORATION (US) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | PHOSPHO1, PLTP, PLA2G2C | SIGMAR1 1462/4885LPAR3 109/4885LPAR1 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.