Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391196 | 0.75 | HTR2A (0.36) | KDM4EADORA2AADORA1ADORA3MAPK14 | |
| SCHEMBL3391217 | 0.74 | MEN1 (0.31) | L3MBTL1 | |
| SCHEMBL3389193 | 0.69 | CCR1 (0.37) | KDM4EALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3391256 | 0.68 | CCR1 (0.52) | ADORA2AADORA1MAPK14 | |
| SCHEMBL8776954 | 0.67 | CYP1A2 (0.48) | ADORA2AADORA1MAPK14LMNASMN1; SMN2 | |
| SCHEMBL2977002 | 0.64 | CDK5 (0.38) | KDM4ELMNAHTT | |
| SCHEMBL1259949 | 0.64 | ALDH1A1 (0.44) | KDM4EADORA2AADORA1MAPK14ALDH1A1 | |
| SCHEMBL13888925 | 0.63 | STIM1 (0.40) | ADORA2AADORA1MAPK14ALDH1A1LMNA | |
| SCHEMBL5014341 | 0.61 | KDM4E (0.42) | KDM4EADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL12892628 | 0.61 | MAPK14 (0.41) | KDM4EADORA2AADORA1MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| CN-101460479-A | 3-(pyridin-2-yl)-[1,2,4]-triazines for use as fungicides | BASF SE (DE) | 2009-06-17 | — | — | CN | disclosed |
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-04-30 | — | — | US | disclosed |
| EP-2010514-A1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007116078-A1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2007-10-18 | — | — | WO | disclosed |
| WO-2007116078-A1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111692-A1 | 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides | CBR3, CBR1, TH | KDM4E 1789/4885ADORA2A 732/4885ADORA1 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.