Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 8/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651050 | 0.77 | MEN1 (0.74) | SMN1; SMN2HTTNPC1POLBESR1 | |
| SCHEMBL2366947 | 0.77 | MAPT (0.56) | SMN1; SMN2HTTNPC1POLBESR1 | |
| SCHEMBL3396830 | 0.77 | HPGD (0.58) | SMN1; SMN2NPC1MEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29042444 | 0.76 | MEN1 (0.72) | SMN1; SMN2HTTNPC1POLBESR1 | |
| SCHEMBL6249556 | 0.76 | CDK5 (0.70) | SMN1; SMN2HTTNPC1POLBESR1 | |
| SCHEMBL3395871 | 0.74 | EPHX2 (0.58) | SMN1; SMN2NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL6335118 | 0.71 | MAPK13 (0.56) | SMN1; SMN2NPC1POLBMEN1KMT2A | |
| SCHEMBL5836589 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTNPC1POLBESR1 | |
| SCHEMBL3398516 | 0.69 | RAB9A (0.58) | SMN1; SMN2HTTNPC1POLBMEN1 | |
| SCHEMBL3397250 | 0.69 | RAB9A (0.61) | SMN1; SMN2NPC1POLBHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | SMN1; SMN2 2662/4885HTT 3579/4885NPC1 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.