Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395871 | 0.77 | EPHX2 (0.58) | HPGDKMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3394448 | 0.77 | SMN1; SMN2 (0.58) | HPGDLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24953869 | 0.75 | MEN1 (0.55) | HPGDLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2367246 | 0.74 | TNIK (0.65) | HPGDLMNAKMT2AMAPT | |
| SCHEMBL3021548 | 0.74 | LMNA (0.86) | HPGDLMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3393541 | 0.72 | CACNA1B (0.56) | HPGDKMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3398516 | 0.72 | RAB9A (0.58) | LMNAKMT2ASMN1; SMN2MAPK13MAPK12 | |
| SCHEMBL3394933 | 0.72 | CSNK2A2 (0.60) | LMNAKMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3390828 | 0.72 | MEN1 (0.56) | LMNAKMT2ASMN1; SMN2MAPK13MAPK12 | |
| SCHEMBL11590223 | 0.71 | CCNE1 (0.57) | HPGDKMT2AALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | HPGD 2756/4885LMNA 4362/4885KMT2A 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.