Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827334 | 1.00 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL31622487 | 0.97 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL20917421 | 0.86 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL20917423 | 0.86 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL19204835 | 0.84 | SLC1A2 (0.50) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL138281 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL1706675 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL27757196 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL138280 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL394192 | 0.83 | ALDH1A1 (0.49) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120158434-A | Carbonyl reductase mutant and application thereof in synthesis of posaconazole intermediate | 中国科学院天津工业生物技术研究所 | 2025-06-17 | — | — | CN | claimed |
| CN-119591481-A | Method for synthesizing posaconazole intermediate (2S) -2-benzyloxy-3-pentanone | 北京联本医药化学技术有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-118684567-A | Method for synthesizing (2S) -2-benzyloxy-3-pentanone | 安庆北化大科技园有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-112063680-B | Biological catalysis preparation method of posaconazole intermediate (2S,3R) -2-benzyloxy-3-pentanol | 甘肃皓天医药科技有限责任公司 | 2022-05-20 | — | — | CN | claimed |
| CN-112063680-A | Biological catalysis preparation method of posaconazole intermediate (2S,3R) -2-benzyloxy-3-pentanol | 甘肃皓天医药科技有限责任公司 | 2020-12-11 | — | — | CN | claimed |
| WO-2019077627-A1 | A PROCESS FOR THE MANUFACTURE OF POSACONAZOLE | METROCHEM API PVT LTD. (IN) | 2019-04-25 | — | — | WO | claimed |
| CN-121496018-A | Preparation method of N' - ((2S, 3S) -2- (benzyloxy) penta-3-yl) formylhydrazinium oxalate enzyme | 张家口市格瑞高新技术有限公司 | 2026-02-10 | — | — | CN | disclosed |
| CN-120158434-B | Carbonyl reductase mutant and application thereof in synthesis of posaconazole intermediate | 中国科学院天津工业生物技术研究所 | 2025-09-02 | — | — | CN | disclosed |
| CN-120158434-A | Carbonyl reductase mutant and application thereof in synthesis of posaconazole intermediate | 中国科学院天津工业生物技术研究所 | 2025-06-17 | — | — | CN | disclosed |
| CN-120158434-A | Carbonyl reductase mutant and application thereof in synthesis of posaconazole intermediate | 中国科学院天津工业生物技术研究所 | 2025-06-17 | — | — | CN | disclosed |
| CN-119591481-A | Method for synthesizing posaconazole intermediate (2S) -2-benzyloxy-3-pentanone | 北京联本医药化学技术有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119591481-A | Method for synthesizing posaconazole intermediate (2S) -2-benzyloxy-3-pentanone | 北京联本医药化学技术有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-118684567-A | Method for synthesizing (2S) -2-benzyloxy-3-pentanone | 安庆北化大科技园有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-103193609-B | Synthesizing process of (S)-2-benzyloxy-pentan-3-one | ZHEJIANG PEGENT CHEMICAL CO., LTD. (CN) | 2014-10-08 | — | — | CN | disclosed |
| CN-103936564-A | Method for preparing (2S, 3R)-2-benzyloxy-3-pentanol as intermediate of posaconazole | JINAN KANGHE MEDICAL TECHNOLOGY CO LTD | 2014-07-23 | — | — | CN | disclosed |
| CN-103819321-A | Preparation method of (S)-2- benzyloxy-3-pentanone | TIANJIN CHEMIWAY BIOPHARMER TECH DEV CO LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-103819321-A | Preparation method of (S)-2- benzyloxy-3-pentanone | TIANJIN CHEMIWAY BIOPHARMER TECH DEV CO LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-103193609-A | Synthesizing process of (S)-2-benzyloxy-pentan-3-one | ZHEJIANG REGEN CHEMICAL CO LTD | 2013-07-10 | — | — | CN | disclosed |
| CN-103193609-A | Synthesizing process of (S)-2-benzyloxy-pentan-3-one | ZHEJIANG REGEN CHEMICAL CO LTD | 2013-07-10 | — | — | CN | disclosed |
| WO-2012003147-A1 | ISOINDOLONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2012-01-05 | — | — | WO | disclosed |