Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231110 | 0.85 | SLC1A1 (0.59) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL3394524 | 0.84 | SLC1A3 (0.47) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL8827334 | 0.84 | SLC1A3 (0.47) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| Hydrochloric Acid SCHEMBL9760378 | 0.83 | SLC1A1 (0.58) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL5408336 | 0.82 | ALDH1A1 (0.53) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL31622487 | 0.81 | SLC1A3 (0.45) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL8329553 | 0.81 | L3MBTL1 (0.51) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL1749347 | 0.79 | SLC1A1 (0.57) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL28709606 | 0.78 | SLC1A3 (0.45) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 | |
| SCHEMBL8329550 | 0.77 | L3MBTL1 (0.54) | SLC1A2SLC1A1KMT2ASLC1A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |