Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365828 | 0.80 | SCN9A (0.42) | PRKCAMMP12SCN9ACYP3A4CYP2D6 | |
| SCHEMBL3598982 | 0.71 | PRKCA (0.37) | PRKCAMMP12S1PR1 | |
| SCHEMBL3087212 | 0.64 | PRKCA (0.33) | PRKCAMMP12CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6208157 | 0.63 | SCN9A (0.43) | SCN9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3583062 | 0.63 | PRKCA (0.41) | PRKCAMMP12SCN9ACYP3A4CYP2C9 | |
| SCHEMBL4821691 | 0.62 | CNR2 (0.41) | PRKCAMMP12SCN9ACYP3A4CYP2D6 | |
| SCHEMBL14263455 | 0.62 | PRKCA (0.40) | PRKCAMMP12SCN9ACYP3A4CYP2D6 | |
| SCHEMBL27713477 | 0.62 | PRKCA (0.40) | PRKCAMMP12SCN9ACYP3A4CYP2D6 | |
| SCHEMBL3593841 | 0.61 | PTGDR2 (0.33) | — | |
| SCHEMBL3361180 | 0.61 | PARP1 (0.44) | PRKCAMMP12S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987038-B1 | HCV NS5B INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2010-10-06 | — | — | EP | disclosed |