Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 9/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 8/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 6/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 5/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | HTR1B | P28222 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Yohimbine SCHEMBL9622911 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL10020758 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL18120971 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL564078 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL25366080 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL8097702 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL23244673 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL13932206 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL22703462 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL4548294 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 13201 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144798-A1 | Disruption of Vascular Smooth Muscle Relaxation by Carfilzomib May be the Primary Reason for CFZ-Induced Vascular Dysfunction | AMGEN INC. (US) | 2026-05-28 | — | — | US | claimed |
| CN-122056948-A | Uncaria alkaloid extract and preparation method and application thereof | 华南理工大学 | 2026-05-19 | — | — | CN | claimed |
| EP-4725483-A1 | COMBINATION COMPRISING AT LEAST ONE 5-HT2A RECEPTOR ANTAGONIST AND AT LEAST ONE 5-HT3 RECEPTOR ANTAGONIST AND ITS MEDICAL USE | Université de Bordeaux (FR) | 2026-04-15 | — | — | EP | claimed |
| EP-4724125-A1 | APPARATUS, METHODS, AND SYSTEMS FOR ATOMIZED DELIVERY OF A COMPOSITION TO A PATIENT | Microneb Tech Holdings, Inc. (US) | 2026-04-15 | — | — | EP | claimed |
| US-12533327-B2 | Hexylamine salts and methods of using hexylamine | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-01-27 | — | — | US | claimed |
| EP-4676470-A2 | DILEUCINE COMPOSITIONS AND METHODS OF USE THEREOF | Ingenious Ingredients, LP (US) | 2026-01-14 | — | — | EP | claimed |
| US-20250367206-A1 | 1-METHYLXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF | Ingenious Ingredients, LP (US) | 2025-12-04 | — | — | US | claimed |
| US-20250360137-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | FREEDOM BIOSCIENCES INC (US) | 2025-11-27 | — | — | US | claimed |
| WO-2025229086-A1 | ADHESIVE COSMETIC COMPOUNDS AND USES THEREOF | SKINOSIVE (FR) | 2025-11-06 | — | — | WO | claimed |
| US-12434068-B2 | Accessing spinal networks to address sexual dysfunction | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-07 | — | — | US | claimed |
| EP-0236251-A2 | 2-(2-aminobenzyl)-1,2,3,4-tetrahydroisoquinolines, processes for obtaining them and pharmaceutical compositions containing them | UNIVERSITE LOUIS PASTEUR (STRASBOURG I) (FR) | 1987-09-09 | — | — | EP | claimed |
| US-4659714-A | PROLONGATION WITH VASOCONSTRICTORS; REVERSAL WITH ADRENERGIC BLOCKING AGENTS | DENTSPLY, LTD. (GB) | 1987-04-21 | — | — | US | claimed |
| EP-0217688-A1 | Peptide derivatives with a lactonic or cycloamidic structure, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1987-04-08 | — | — | EP | claimed |
| US-4588724-A | Treatment for selective reduction of regional fat deposits | GREENWAY FRANK L III (US) | 1986-05-13 | — | — | US | claimed |
| EP-0160191-A1 | Kit for treating mammals | Dentsply Limited (GB) | 1985-11-06 | — | — | EP | claimed |
| US-4532135-A | Treating renal damage by administering vasodilator having postsynaptic alpha-adrenoceptor blocking activity and antihyperlipidemic characteristics | EDWARDS K DAVID G | 1985-07-30 | — | — | US | claimed |
| EP-0120165-A2 | A preparation and a process for achieving regional weight control | Greenway III, Frank L. (US) | 1984-10-03 | — | — | EP | claimed |
| EP-0105361-A1 | ANTAGONISM OF CENTRAL NERVOUS SYSTEM DRUGS BY THE ADMINISTRATION OF 4-AMINOPYRIDINE ALONE OR IN COMBINATION WITH OTHER DRUGS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1984-04-18 | — | — | EP | claimed |
| WO-1983003541-A1 | ANTAGONISM OF CENTRAL NERVOUS SYSTEM DRUGS BY THE ADMINISTRATION OF 4-AMINOPYRIDINE ALONE OR IN COMBINATION WITH OTHER DRUGS | UNIV GEORGIA RES FOUND (US) | 1983-10-27 | — | — | WO | claimed |
| US-4310524-A | TCA Composition and method for rapid onset antidepressant therapy | RICHARDSON-MERRELL, INC. (US) | 1982-01-12 | — | — | US | claimed |