SCHEMBL3395482

SCHEMBL3395482

Oc1ccccc1C=Nc1ccccc1N=Cc1ccccc1O.[LiH].[LiH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.96
CA2 P00918 7/20 0.96
CA9 Q16790 6/20 0.96
SIRT2 Q8IXJ6 1/20 0.67
KDM4E B2RXH2 5/20 0.56
ALDH1A1 P00352 4/20 0.56
MAPT P10636 4/20 0.56
POLB P06746 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MPI P34949 1/20 0.56
RECQL P46063 1/20 0.56
ALOX15 P16050 2/20 0.56
GAA P10253 2/20 0.56
USP2 O75604 1/20 0.56
ALOX12 P18054 1/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 1/20 0.56
HPGD P15428 2/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710476 0.98 CA12 (1.00) CA12CA2CA9SIRT2KDM4E
SCHEMBL30361105 0.98 CA12 (1.00) CA12CA2CA9SIRT2KDM4E
SCHEMBL29359256 0.98 CA12 (1.00) CA12CA2CA9SIRT2KDM4E
SCHEMBL710477 0.98 CA12 (1.00) CA12CA2CA9SIRT2KDM4E
SCHEMBL803089 0.98 CA12 (1.00) CA12CA2CA9SIRT2KDM4E
SCHEMBL25379604 0.96 CA12 (0.96) CA12CA2CA9SIRT2KDM4E
SCHEMBL4774107 0.96 CA12 (0.96) CA12CA2CA9SIRT2KDM4E
SCHEMBL31540902 0.96 CA12 (0.96) CA12CA2CA9SIRT2KDM4E
Water SCHEMBL1451343 0.94 CA12 (0.92) CA12CA2CA9SIRT2KDM4E
Water SCHEMBL1451344 0.94 CA12 (0.92) CA12CA2CA9SIRT2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9437828-B2 Electroluminescent device using azomethine-lithium-complex as electron injection layer MERCK PATENT GMBH (DE) 2016-09-06 US disclosed
US-20150065725-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
US-8883325-B2 Electroluminescent device using azomethine-lithium-complex as electron injection layer MERCK PATENT GMBH (DE) 2014-11-11 US disclosed
US-20120205638-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER MERCK PATENT GMBH (DE) 2012-08-16 US disclosed
EP-2095690-B1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER MERCK PATENT GMBH (DE) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120205638-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER ACSL3, APOL1, INTS9 CA12 4003/4885CA2 2621/4885CA9 2356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.